Analysis of application of human albumin after hepatectomy for primary liver cancer
10.3969/j.issn.1006-0111.2015.05.023
- VernacularTitle:人血白蛋白在原发性肝癌肝切除术后的应用分析
- Author:
Qi ZHAN
1
;
Yueyue LI
;
Xiaojun WANG
;
Anni CHEN
;
Suli GU
;
Guoqing ZHANG
Author Information
1. 第二军医大学东方肝胆外科医院药材科
- Keywords:
human serum albumin;
hepatectomy;
liver function;
Child-Pugh classification
- From:
Journal of Pharmaceutical Practice
2015;(5):463-466
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the use of human albumin (ALB) after hepatectomy in hepatocellular carcinoma patients in our hospital .Methods 150 hospital medical records from June 2012 to June 2013 were analyzed ,which used the human ser-um albumin during the perioperative period of hepatectomy at hepatocellular carcinoma (preoperative Child-Pugh A or B) retro-spectively ,the rationality of human blood albumin use was evaluated .Results Among the 150 medical records ,the total appli-cation amount of albumin was 11 212 .5 g (897 bottles) ,the total cost was 527 ,744 yuan ,nearly 20 percent of total drug costs ,accounting for nearly 10% of the total cost of hospitalization .By using human serum albumin after surgery ,the patients'liver function was significantly improved (P<0 .05) ,there was a positive correlation between the Child-Pugh score and dosage of human albumin (P<0 .05) .Conclusion The use of human serum albumin was rational during the perioperative period of hepatectomy in hepatocellular carcinoma patients in our hospital ,which had achieved the desired therapeutic effect .