One case of double primary tumors with secondary acute leukemia induced by chemotherapy drugs and literature review
10.3969/j.issn.1006-0111.2015.05.020
- VernacularTitle:化疗药物治疗双原发肿瘤继发急性白血病1例及文献复习
- Author:
Xijing YANG
1
;
Fuping ZHOU
;
Qian ZHANG
;
Qijun QIAN
Author Information
1. 东方肝胆外科医院肿瘤生物治疗科
- Keywords:
secondary leukemia;
ovarian cancer;
breast cancer;
chemotherapy
- From:
Journal of Pharmaceutical Practice
2015;(5):453-456
- CountryChina
- Language:Chinese
-
Abstract:
In recent years ,with a large number of chemotherapy development ,the incidence of secondary leukemia in-creased year by year ,an acute myelomonocytic leukemia after chemotherapy and radiotherapy in 1 case of ovarian cancer and breast cancer was reported .The time from first chemotherapy to acute leukemia onset was 37 months .This patient had rapid onset and short survival period .Reports in the literature suggested that alkylating agents ,topoisomerase I inhibitors ,platinum were all easy to induce secondary leukemia .Hematopoietic stem cell transplantation coud reduce mortality and prolong progres-sion free survival .
