Treatment analysis of liver cirrhosis with hepatitis B complicated by subcutaneous panniculitis-like T-cell lymphoma associated hemophagocytic syndrome

VernacularTitle:乙肝肝硬化并发皮下脂膜炎样 T细胞淋巴瘤伴噬血细胞综合征的治疗分析
Author: Xijng YANG ¹ ; Fuping ZHOU ; Qian ZHANG ; Qijun QIAN
Author Information

1. 第二军医大学附属东方肝胆外科医院生物治疗科
Keywords: subcutaneous panniculitis-like T-cell lymphoma; hemophagocytic syndrome; cirrhosis; entecavir
From: Journal of Pharmaceutical Practice 2015;(4):363-365
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical features and treatment of liver cirrhosis with hepatitis B complicated by subcutaneous panniculitis-like T-cell lymphoma (SPTCL) associated hemophagocytic syndrome (HPS) .Methods A retrospec-tive analysis of case clinical data with liver cirrhosis complicated by SPTCL associated HPS was done in August 2014 in our hospital .Results Because of different phenotypes of T cell receptor (TCR) ,the aggression ,treatment response and prognosis of the disease were significantly different .The patients with HPS had poor treatment effect and short survival period .Conclu-sion Liver cirrhosis with hepatitis B complicated by SPTCL associated HPS is rare ,Bone marrow morphology ,pathology , immunohistochemistry and gene rearrangement detection as soon as possible are important for early diagnosis .To control HBV early and effectively is particularly important .Early diagnosis and treatment are important to prolong survival .