Research on the technological process and methods of the comprehensive pharma-ceutical experiment of rutin tablets
10.3969/j.issn.1006-0111.2015.04.018
- VernacularTitle:芦丁片剂药学综合性实验的流程及方法研究
- Author:
Li CHEN
1
;
Hongli DU
;
Rentao ZENG
;
Yeye ZHANG
;
Ying LU
;
Guojun CAI
Author Information
1. 第二军医大学药学院
- Keywords:
multidisciplinary experiments;
rutin;
pharmacodynamics;
tablets
- From:
Journal of Pharmaceutical Practice
2015;(4):359-362
- CountryChina
- Language:Chinese
-
Abstract:
Objective To imitate the development process of new drugs with rutin as the model and to do multidiscipli-nary experiments of preparation and pharmacodynamics of rutin tablets .Methods Thin-layer chromatography was used to i-dentify rutin in Pagodatree flower bud .High-performance liquid chromatography was used for quantitative determination of ru-tin in Pagodatree flower bud and rutin products .The vasodilatation effect of rutin was investigated .The preparation of rutin tablets was completed .Results and Conclusion We completed the identification of Pagodatree flower bud ,extraction and puri-fication of rutin from Pagodatree flower bud ,the assay of rutin ,the pharmaco-dynamics study and the formulation of rutin tab-lets .The experiments helped the postgraduates to be familiar with the research process of new drugs and to improve their ex-perimental operation skills .
