Total synthesis of the natural product of crinumaquine
10.3969/j.issn.1006-0111.2015.04.011
- VernacularTitle:天然产物文殊兰新碱的全合成研究
- Author:
Hao CHEN
1
;
Ji YE
;
Jiangyun LIU
;
Weidong ZHANG
;
Qingyan SUN
Author Information
1. 苏州大学药学院
- Keywords:
alkaloid;
crinumaquine;
total synthesis
- From:
Journal of Pharmaceutical Practice
2015;(4):331-333
- CountryChina
- Language:Chinese
-
Abstract:
Objective To complete the synthesis of the natural product of crinumaquine .Methods 3 ,4-methylenedioxy-phenethylamine and 2 ,5-dimthoxyphenylacetic were taken as starting material ,and chemical reactions of condensation ,cycliza-tion ,reduction ,oxidation and other reactions were conducted .Results and Conclusion The optimum synthetic route was deter-minedunder which the final yield rate was 73% .
