Fungistasis of nanometer silvers synthesized by different methods on Candida al-bicans
10.3969/j.issn.1006-0111.2015.04.010
- VernacularTitle:不同制法纳米银的抗真菌活性研究
- Author:
Lulu ZHANG
1
;
Qi MIAO
;
Zhaojiao YE
;
Hongjiao LI
;
Yuanying JIANG
;
Yongbing CAO
Author Information
1. 第二军医大学药学院
- Keywords:
silver nanoparticles;
Candida albicans;
fungistasis
- From:
Journal of Pharmaceutical Practice
2015;(4):328-330,358
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the in vitro fungistasis of nanometer silvers made by different methods on Candida al-bicans .Methods The minimal inhibitory concentrations (MICs) of Candida albicans strains stimulated to silver nanoparticles were determined by microdilution method .The combination effects of silver nanoparticles with fluconazole were determined by chess board check assay .Results The inhabitation effect of two kinds of silver nanoparticles were different on the growth of Candida albicans .Silver nanoparticles had a synergistic effect with fluconazole on Candida albicans .Conclusion The two kinds of silver nanoparticles had various antifungal activities in vitro and had a synergistic effect with fluconazole on Candida albicans .
