Study on anti-microbial activity of allicin on campylobacter jejuni
10.3969/j.issn.1006-0111.2015.02.014
- VernacularTitle:大蒜素对空肠弯曲杆菌抑菌作用的研究
- Author:
Hongtao PAN
1
;
Zongxing YANG
;
Wencui ZHAO
;
Yanping WANG
;
Haiyan SONG
;
Qi ZHANG
Author Information
1. 解放军208医院
- Keywords:
allicin;
ciprofloxacin;
erythromycin;
MIC;
bacteriostatic rate
- From:
Journal of Pharmaceutical Practice
2015;(2):147-149,170
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the anti‐microbial activity and strength of allicin on Campylobacter jejuni .Methods Disc diffusion method (K‐B) was used to determine the diameter of the bacteriostatic ring .The minimal inhibitory concentra‐tion (MIC) of allicin ,ciprofloxacin and erythromycin were detected by constant broth dilution method ,respectively .The mini‐mal inhibitory concentrations and bacteriostatic rate of allicin ,ciprofloxacin and erythromycin were compared .Results The anti‐microbial activity on Campylobacter jejuni of allicin (MIC 12 .8 μg/ml ,bactetiostatic rate 90 .40% ) was better than that of ciprofloxacin (MIC 20 .48 μg/ml ,bactetiostatic rate 90 .21% ) and erythromycin (MIC 35 .84 μg/ml ,bactetiostatic rate 90 . 33% ) .Conclusion Allicin has anti‐microbial activity on Campylobacter jejuni in vitro .
