Meta-analysis on clinical study of western routine treatments combined with Tongxinluo capsule in treatment of angina pectoris
10.3969/j.issn.1006-0111.2015.01.024
- VernacularTitle:西药常规治疗联用通心络胶囊治疗冠心病心绞痛疗效的荟萃分析
- Author:
Rong FAN
1
;
Tianshu REN
;
Qingchun ZHAO
;
Guobing SHI
Author Information
1. 沈阳军区总医院药剂科
- Keywords:
combination of Chinese and western medicine;
angina pectoris;
efficacy;
Meta-analysis
- From:
Journal of Pharmaceutical Practice
2015;(1):83-87
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the effectiveness of western routine treatments combined with Tongxinluo capsule for angina pectoris .Methods The randomized controlled trials(RCTs ) of western routine treatments combined with tongxinluo capsule for angina pectoris were collected through searching on computer from the following databases ,CNKI (2000 -2011 ) ,WanFang Data (2000 -2011) ,WeiPu Data(2000-2011) ,PubMed(2000-2011) and manual search relevant journals ,conference papers .Results A total of 11 studies were included and improvement rate of abnormal ECG were estimated in 9 studies and improvement rate of symptoms of angina were estimated in 11 studies .ECG clinical evaluation of the treatment group relative to the control group ,relative risk (RR) value was 1 .40 (95% CI:1 .28‐1 .54) ,P<0 .01 ,symptoms of angina clinical evaluation ,treatment group relative to the control group RR value of 1.25 (95% CI:1 .18‐1 .32) ,P<0 .01 .Only slight gastrointestinal discomfort were found in treatment group .Conclusion Tongxinluo capsule in combination on the basis of conventional western treatment could effectively improve the clinical efficacy and drug safety .
