Mechanism s of damga e and treatments of cerebral ischemia and reperfusion
10.3969/j.issn.1006-0111.2014.06.001
- VernacularTitle:脑缺血和再灌注损伤与防治机制的研究进展
- Author:
Jinhua WU
1
;
Huiping MA
;
Ping MENG
;
Zhengping JIA
Author Information
1. 兰州军区兰州总医院
- Keywords:
cerebral ischemia;
reperfusion damage;
prevention and treatment;
mechanism of damage
- From:
Journal of Pharmaceutical Practice
2014;(6):401-404,447
- CountryChina
- Language:Chinese
-
Abstract:
To summarize the advances in mechanisms of damage and treatments of cerebral ischemia and reperfusion and fore -casts future research directions .The existing achievements in literatures were summarized .Cerebral ischemia and reperfusion damage were related to inflammatory response , intracellular calcium overload , free radicals injury , release of excitatory amino acids and other factors.The treatments included reducing ischemia time , blocking glutamate receptors , free radical scavenging , inhibition of apoptosis , reducing inflammation , and promoting neuronal growth , etc.Multi-target treatment would be future directions in treatment of cerebral ischemia.
