Effect of Xinnaoning tablet on blood stasis model in rats
10.3969/j.issn.1006-0111.2014.05.012
- VernacularTitle:心脑宁片对大鼠血瘀模型的影响
- Author:
Shaojun HAO
1
;
Hongdi LV
;
Jun LI
;
Feng SU
;
Zhengchen ZHANG
Author Information
1. 解放军371中心医院
- Keywords:
Xinnaoning tablets;
blood stasis rat model;
Naoan tablets
- From:
Journal of Pharmaceutical Practice
2014;(5):360-361,388
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of Xinnaoning tablets on blood stasis rat model which was caused to dexamethasone sodium phosphate injection with symptom score , K-value of blood, modified index, electrophoresis index.Methods 60 rats, were di-vided into 6 groups stochastically , and 1 group for vacuity contrast group , the other 5 groups for blood stasis model , the 5 groups were model group , Naoan tablets group , high dose , medium dose and low dose Xinnaoning tablets groups .Symptom score were evaluated , K-value of blood , Modified index , Electrophoresis index were measured .Results The Model was constructed successfully , model group and administrate groups had significant blood symptoms (P<0.01).The effect of high dose Xinnaoning tablets group to blood stasis rat model which was caused to dexamethasone sodium phosphate injection was best .High dose and medium dose Xinnaoning tab-lets groups could induce K-value significantly (P<0.01).Xinnaoning tablets groups could improve modified index and electrophore-sis index significantly (P<0.01), and the effect of high dose and medium dose Xinnaoning tablets groups to blood stasis rat model which was caused to dexamethasone sodium phosphate injection were better .Conclusion Xinnaoning tablets had good improvement effect on blood stasis .
