Study on the identification of raceanisodamine tablets by near infrared spectros-copy
10.3969/j.issn.1006-0111.2014.05.011
- VernacularTitle:消旋山莨菪碱非铝塑包装片剂近红外鉴别模型的初探
- Author:
Yanhua JIA
1
;
Chengwen XIONG
Author Information
1. 解放军总医院第一附属医院药剂药理科
- Keywords:
raceanisodamine tablets;
near infrared;
tablets
- From:
Journal of Pharmaceutical Practice
2014;(5):357-359
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop an identification model of raceanisodamine tablets by diffuse reflection near -infrared spec-troscopy and pattern recognition .Methods The diffuse reflectance spectra in the 12 000-4 000 cm-1 spectral coverage range of racean-isodamine tablets from eight different pharmaceutical factories were collected to establish the identification model .A mono-component near infrared model was established for raceanisodamine tablets .Results The parameters of the identification model for the raceaniso-damine tablets was as follows:spectral range was 5 400-7 000 cm-1 ,the pretreatment method was first derivative and normalization;the threshold was 0.603.And the model was validated , which met the requirements of application .Conclusion The results showed that identification model for the raceanisodamine tablets by near infrared spectroscopy was feasible , which provided a reference method for the model updating .
