Advance in anti-cancer lead-compounds derived from natural products
10.3969/j.issn.1006-0111.2014.05.005
- VernacularTitle:来源于天然产物的抗肿瘤先导结构研究进展
- Author:
Shanchao WU
1
;
Chunquan SHENG
;
Wannian ZHANG
Author Information
1. 第二军医大学药学院
- Keywords:
natural products;
anti-cancer lead-compounds;
anti-cancer activity;
mechanism of action;
structure and activity relationship
- From:
Journal of Pharmaceutical Practice
2014;(5):337-341,371
- CountryChina
- Language:Chinese
-
Abstract:
Cancer is a serious threat to human life and health .Therefore, there is an emergent need to develop novel anti-cancer agents with new structural type , new mechanism of action and higher efficacy .Natural products had played a key role in the dis-covery of anticancer agents .The anti-cancer activity , mechanism of action , structure and activity relationship of several lead-com-pounds which were derived from natural products were summarized in this review .
