Progress on solid self-microemulsifying drug delivery system for oral administration
10.3969/j.issn.1006-0111.2014.04.005
- VernacularTitle:口服固体自微乳化给药系统的研究进展
- Author:
Jiali ZHAO
1
;
Xu WEN
;
Jing ZHANG
;
Jianqing LIU
;
Hongtao SONG
Author Information
1. 南京军区福州总医院药学科
- Keywords:
S-SMEDDS;
solidification technology;
oral bioavailability
- From:
Journal of Pharmaceutical Practice
2014;(4):257-260
- CountryChina
- Language:Chinese
-
Abstract:
Objective To review the newly developed solid self-microemulsifying drug delivery system (S-SMEDDS).Meth-ods Relevant literatures at home and abroad in recent years were consulted and summarized .Results Solid self-microemulsions car-rier, solidification technology and controlled release formulations were discussed , in order to provide relevant references for improving the bioavailability of water-insoluble drugs and the SMEDDS technology for drug release characteristics .Conclusion The utilization of the solid self-emulsifying drug delivery system could significantly enhance the oral bioavailability of water -insoluble drugs .As a new formulation, S-SMEDDS presented huge potential .
