Advances in TOR pathway in Candida albicans
10.3969/j.issn.1006-0111.2014.04.002
- VernacularTitle:白色念珠菌TOR信号转导通路研究现状
- Author:
Huajun LIANG
1
;
Lan YAN
;
Yongbing CAO
;
Yuanying JIANG
;
Tianhua YAN
Author Information
1. 中国药科大学药学院
- Keywords:
Candid a albicans;
target of rapamycin;
rapamycin;
virulence
- From:
Journal of Pharmaceutical Practice
2014;(4):246-249,287
- CountryChina
- Language:Chinese
-
Abstract:
The target of rapamycin ( TOR) , a Ser/Thr protein kinase of PIKKs ( phosphatidylinositol kinase-related kinases ) , is the central factor of a highly conserved signaling pathway in eukaryotes , and regulates cell growth in response to nutrients , hor-mones, and stresses.It controls temporal growth by activating anabolic processes such as translation , ribosome biogenesis , protein syn-thesis, transportation of amino acid and metabolic enzymes .The advances in TOR pathway in the most pervasive human fungal patho-gen Candida albicans.
