Research progress in structural modification and pharmacological activities of berberine
10.3969/j.issn.1006-0111.2014.03.003
- VernacularTitle:小檗碱的结构改造及其药理活性的研究进展
- Author:
Xin JIN
1
;
Xia SONG
;
Yongbin CAO
;
Yuanying JIANG
;
Qingyan SUN
Author Information
1. 福建中医药大学
- Keywords:
berberine derivates;
structure-function relationship;
pharmacological activities
- From:
Journal of Pharmaceutical Practice
2014;(3):171-175
- CountryChina
- Language:Chinese
-
Abstract:
Berberine was an isoquinoline type alkaloid extracted from Chinese herbs such as Coptis chinensis.Recently, as a great many berberine derivatives had been synthesized with comprehensive physiological functions , the structural modification and ap-plication of berberine showed great promising significance .Recent literatures had been systematically analyzed and summarized in this review.With abundant pharmacological activities of berberine different sites ′derivatives had been presented , systematical information of berberine structural modification as a lead compound and new drug R&D were provided in this article .
