Preparation of compound clemastine cream and its clinical efficacy for the treatment of seasonal contact dermatitis in the face

VernacularTitle:复方氯马斯汀霜制备和治疗季节性面部接触性皮炎的临床疗效
Author: Xian-Qi HUANG ¹ ; Guan-Yong LI ; Hua ZHANG
Author Information

1. 解放军济南军区总医院
Keywords: copound clemastine cream; seasonal contact dermatitis; clinical efficacy
From: Journal of Pharmaceutical Practice 2001;19(2):73-74
CountryChina
Language:Chinese
Abstract: OBJECTIVE：To prepare compound clemastine cream(COC)and to evaluate its clinical efficacy for the treatment of seasonal contact dermatitis in the face.METHODS:The preparation was obtained by traditional o/w method.94 outpatients and inpatients were randomly divided into active group(COC group)and control group(Kangfulire ointment group).RESULTS:The healing rate and the total efficient rate were significantly higher than those of control group(p＜0.01，p＜0.05).CONCLUSION:COC has reliable clinical efficacy and has little side effects,so it is one of the specific preparations for the treatment of contact dermatitis and it can be widely used in the clinics.