Immunological characteristics and treatment of pediatric adenovirus pneumonia
10.3760/cma.j.issn.1673﹣4912.2019.10.007
- VernacularTitle:儿童腺病毒肺炎免疫学特点及免疫学治疗方法
- Author:
Wenliang SONG
1
;
Chunfeng LIU
Author Information
1. 中国医科大学附属盛京医院儿科重症监护病房﹐沈阳 110004
- Keywords:
Adenovirus pneumonia;
Children;
Immunology;
Treatment
- From:
Chinese Pediatric Emergency Medicine
2019;26(10):746-751
- CountryChina
- Language:Chinese
-
Abstract:
Adenovirus is a common cause of respiratory infection in children and can cause severe pneumonia. Adenovirus can also cause damage to immune system. It can cause decrease in T and B cell num﹣ber and function,imbalance of Th1/Th2 cell proportion,but also can cause imbalance of proinflammatory cytokines and anti﹣inflammatory cytokines, further leading to dysfunction of immune system, with severe complications such as severe sepsis and multiple organ and system dysfunction. In this paper we will discuss immune pathogenesis of adenovirus infection and provide suggestion for treatment of adenovirus pneumonia.