Comparative study among total body weight,lean body weight and body surface area adj usted iodine contrast agent dose protocols on liver enhanced CT scans
10.3969/j.issn.1002-1671.2019.11.029
- VernacularTitle:基于全体质量、去脂肪体质量和体表面积计算肝脏CT增强碘对比剂用量的对比研究
- Author:
Maoqing HU
1
;
Fang LONG
;
Wansheng LONG
;
Menghuang WEN
;
Zaiyi LIU
;
Changhong LIANG
Author Information
1. 江门市中心医院放射科
- Keywords:
contrast medium;
computed tomography;
total body weight;
lean body weight;
body surface area
- From:
Journal of Practical Radiology
2019;35(11):1831-1835
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the optimal body size index for the calculation of iodine contrast agent dose required for multiphase liver enhanced CT scans based on the total body weight (TBW),lean body weight (LBW)and body surface area (BSA).Methods Two hundred and twenty enrolled patients were randomly divided into three groups,TBW-group (n＝75),LBW-group (n＝72)and BSA-group (n＝73),and administrated iodine doses were 600 mg I/TBW(kg),780 mg I/LBW(kg)and 22 g I/BSA(m2 ),respectively.All patients had taken upper abdominal plain scans and triple-phase enhanced CT scans.The enhanced values (ΔHU)of the aorta at hepatic arterial phase (HAP),the portal vein and liver parenchyma at portal venous phase (PVP)were compared.The correlation coefficients of adjusted maximal hepatic enhancement(aMHE)with TBW,LBW and BSA in three groups were evaluated,respectively.Results There were no statistical differences in the ΔHU values of the aorta at HAP and the portal vein and liver parenchyma at PVP in the three groups respectively.The smallest variances of the aorta at HAP,the portal vein and liver parenchyma at PVP were found in the LBW group. The aMHE showed mildly positive correlation with TBW (r＝0.230)with a P value of 0.047,but it was consistent with LBW (r＝0.158)and BSA (r＝－0.1 54)with corresponding P values of 0.1 85 and 0.1 9 2 ,respectively.Conclusion Compared with TBW and BSA,iodine contrast agent dose calculated based on the patient’s LBW can improve the patient-to-patient uniformities on aorta,portal vein and liver enhancement during the liver multiphase enhanced CT scans.The LBW is the best body index for the calculation of iodine dose on liver enhanced CT scans.
