Correlation of MRI findings and molecular subtypes of non-mass enhancement breast cancer
10.3969/j.issn.1002-1671.2019.11.012
- VernacularTitle:非肿块强化乳腺癌MR I征象与分子分型的相关性分析
- Author:
Rui JIN
1
;
Bing ZHANG
;
Lin WANG
;
Xin CHEN
;
Xiaohui LI
;
Quanxin YANG
Author Information
1. 西安交通大学第二附属医院影像科
- Keywords:
breast cancer;
non-mass enhancement;
molecular subtype;
magnetic resonance imaging
- From:
Journal of Practical Radiology
2019;35(11):1759-1762
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the correlation between the molecular subtypes of non-mass enhancement (NME)breast cancer and MRI findings.Methods A retrospective analysis of MRI images and clinicopathological data of 62 patients with NME breast cancer who received 3.0T breast MRI multimodal scan from January 201 5 to June 201 9 was conducted.Molecular subtypes were classified by immunohistochemical staining.The differences between MRI findings of NME breast cancer and molecular subtypes were compared by ch-i square test and Fisher exact probability method,and the correlation between them was analyzed by cross contingency table.Results The differences of molecular subtypes of NME breast cancer in the internal enhancement and peritumoral edema were statistically significant (P＜0.05),while the differences in the TIC,lesion distribution type and peritumoral vascular were not statistically significant (P＞0.05).Conclusion Luminal A type was less prone to peritumoral edema in NME breast cancer.Luminal B type was mainly heterogeneous enhancement. HER-2 overexpression type and triple negative type are mainly clustered ring enhancement,and prone to peritumoraledema.Different molecular subtypes of NME breast cancer have certain MRI characteristics,which is expected to provide a non-invasive evaluation for the preoperative treatment of NME breast cancer.
