Chest CT findings of IgG4-related lung disease
10.3969/j.issn.1002-1671.2019.11.009
- VernacularTitle:IgG4相关性肺病的胸部CT表现
- Author:
Feng PAN
1
;
Fei YUAN
;
Yuanyuan ZHANG
;
Tianlong HUO
Author Information
1. 北京大学人民医院放射科
- Keywords:
IgG4-related lung disease;
chest;
computed tomography
- From:
Journal of Practical Radiology
2019;35(11):1747-1750
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the chest CT features of IgG4-related lung disease(IgG4-RLD).Methods The clinical data and chest CT findings of 10 patients with IgG4-RLD diagnosed by the pathological findings of lungs or bronchus were analyzed retrospectively,including masses,nodules,ground glass opacities,pulmonary interlobular septal thickening,bronchovascular bundle thickening,mediastinal lymph nodes enlargement and pleural involvement.Results There were two types of chest CT findings in 10 patients:(1 )Isolated mass/nodule type in 5 patients,presenting as a single lung mass (n=3)and a single lung nodule (n=2),and the lesions were in irregular shape, with shallow lobulated edges and burrs,with no mediastinal lymph nodes enlargement.(2)Interstitial thickening in 5 patients,presenting with thickening of pulmonary lobular septum(n=5)and thickening of bronchovascular bundle(n=4),multiple patchyground glass opacities(n=3), consolidation(n=3),mild mediastinum lymph nodes enlargement(n=3),a little bilateral pleural effusion(n=2)and nodular thickening of pleura(n=2).Serum IgG4 level was increased in 4 cases.Conclusion Chest CT findings of IgG4-RLD can be classified into two types:solitary mass/nodule type and interstitial type.Combing the chest CT manifestation with clinical characteristics will improve the diagnostic accuracy of IgG4-RLD.