Analysis of imaging and skin characteristics of SAPHO syndrome
10.3969/j.issn.1002-1671.2019.10.021
- VernacularTitle:SAP H O 综合征影像和皮肤特征分析
- Author:
Duan SONG
1
;
Mingtuan XUE
Author Information
1. 内蒙古赤峰学院附属医院CT/MRI室
- Keywords:
SAPHO syndrome;
computed tomography;
magnetic resonance imaging;
skin
- From:
Journal of Practical Radiology
2019;35(10):1640-1643
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical and imaging characteristics of synovitis,acne,pustulosis,hyperostosis,osteitis(SAPHO syndrome),to improve the recognition of this disease.Methods Clinical and imaging data were respectively analyzed in 12 SAPHO patients with the review of literature.Results In the 1 2 SAPHO cases,9 were females and 3 were males,with an average age of (45 ±6)years.All the 1 2 cases had bone changes on the anterior-superior chest wall,which manifested as osteosclerosis,hyperplasia and joint destruction.There were 5 cases manifested as symmetrical lesion which were the typical sea gull sign or cow head sign with the proportion of 41.7%.There were 4 cases with the lesion involving the spine including 3 cases in the thoracic vertebra and 1 case in the lumbar vertebra,which showed the erosion and sclerosis in the endplates and destruction of the anterior and posterior vertebral angles.There were 2 cases with the lesion involving the sacroiliac joints,including 1 unilateral and 1 bilateral case,which showed as joint destruction.In the 12 cases,there were 11 cases with obvious cutaneous pathological changes,including palmoplantar pustulosis in 8 cases and acne in 3 cases.Conclusion SAPHO syndrome can be diagnosed by combining skin lesions and bone changes on the patient’s anterior-superior chest wall.
