Progress in research into the genes associated with venous thromboembolism
10.5847/wjem.j.1920-8642.2015.02.003
- Author:
Lian-Xing ZHAO
1
;
Bo LIU
;
Chun-Sheng LI
Author Information
1. Department of Emergency Medicine
- Publication Type:Journal Article
- Keywords:
Venous thrombosis;
Gene;
Hereditary;
Polymoriphism
- From:
World Journal of Emergency Medicine
2015;6(2):100-104
- CountryChina
- Language:English
-
Abstract:
BACKGROUND: Venous thromboembolism (VTE), including both deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common, lethal disorder that affects hospitalized and non-hospitalized patients. This study aimed to review the progress in the research into VTE. DATA SOURCES: We reviewed the studies about VTE and verified different genetic polymoriphisms of VTE. RESULTS: The pathogenesis of VTE involves hereditary and acquired factors. Many studies indicated that the disorder of coagulation and fibirnolytic system is of utmost importance to this disease. Genetic polymoriphism-related VTE demonstrated significant differences among geographies and ethnicities. CONCLUSION: VTE has many risk factors, but genetic factors play an important role.
