The S100 protein family and its application in cardiac diseases
- Author:
Xiu-Jie WANG
1
;
Man WANG
Author Information
1. Department of Emergency Medicine
- Publication Type:Journal Article
- Keywords:
Cardiac function;
S100 proteins;
Markers
- From:
World Journal of Emergency Medicine
2010;1(3):165-168
- CountryChina
- Language:English
-
Abstract:
The S100 protein family is the largest group of EF-hand signaling proteins in humans. The members of the S100 protein family are expressed in many tissues and play different functions. Many diseases are related to S100 proteins, which function as new biochemical markers especially in cardiac diseases. The most studied members, protein S100Β and protein S100A1, exhibit activities in cardiac diseases, and these immunohistochemical expressions or serum levels have been used in predicting neurologic outcome after resuscitation of cardiac arrest or recovery of cardioprotective function.
