Multiple papillary adenomas (PA) coexisting with clear cell renal cell carcinoma (CCRCC):a case report
10.3969/j.issn.1672-8467.2019.05.023
- VernacularTitle:透明细胞肾细胞癌(CCRCC)合并多发性乳头状瘤(PA)1例
- Author:
Xiao-Mu HU
1
;
Zhong-Wen ZHOU
;
Xiang NI
;
Feng TANG
Author Information
1. 复旦大学附属华山医院病理科 上海 200040
- Keywords:
multiple papillary adenoma;
clear cell renal cell carcinoma (CCRCC);
accurate diagnosis
- From:
Fudan University Journal of Medical Sciences
2019;46(5):704-707
- CountryChina
- Language:Chinese
-
Abstract:
Papillary adenoma (PA) of kidney is defined as a lesion measuring less than 15 mm and featuring papillary or tubular architecture along with nuclei of low grade.Clear cell renal cell carcinoma (CCRCC) is the most common seen group of malignant neoplasms consists of cells with clear or eosinophilic cytoplasm.The coexistence of these two kinds of tumor is rare and was only reported in one piece of literature to date.We report a thought-provoking case in which CCRCC is coexisting with multiple PAs.The CCRCC shows no difference with other common cases while the PAs share the same clinical and pathological features with other ones and demonstrates no amplifying of 3,7 or 17 chromosome.However,the multiple PAs were neglected by imaging doctors and surgeons,and some tiny lesions were not found until the observation under microscope.This case reminds that patients accepting partial nephrectomy for CCRCC may have PAs,so attention should be paid to the image studies along with routine pathological examination of kidney for that there may exists two or more kinds of lesions.
