Inappropriate Secretion of Antidiuretic Hormone in a Patient with Squamous Cell Carcinoma of the Lung mimicking Pulmonary Tuberculosis.
- Author:
Soon Je KIM
1
;
Ha Keun RYU
;
Sun Doo KIM
;
Kil Do LEE
;
Bong An PARK
;
Ju Seong RYU
;
Jae Deung YU
Author Information
1. Department of Internal Medicine and Radiology KonKuk University College of Medicine, Chungj u, Korea
- Publication Type:Case Report
- Keywords:
SIADH;
Squamous cell carcinoma of the lung;
ADH;
ANP
- MeSH:
Aged;
Atrial Natriuretic Factor;
Carcinoma, Squamous Cell*;
Humans;
Hyponatremia;
Inappropriate ADH Syndrome;
Lung*;
Osmolar Concentration;
Sodium;
Tuberculosis, Pulmonary*
- From:Journal of the Korean Geriatrics Society
1999;3(4):50-55
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 71-year-old man with squamous cell carcinoma of lung mimicking pulmonary tuberculosis associated with the syndrome of inappropriate secretion of ADH(SIADH). Laboratory examination showed serum sodium concentration of 108 mEq/l. serum osmolality 247 mEg/l urine sodium concentration of 141 mEq/l urine osmolality 547 mEq/l. normal levels (<0.56 pg/ml) of serum antidiuretic hormone (ADH). ADH release was regulated normally with changes in serum osmolality. SIADH was diagnosed on the basis of hyponatremia with corresponding serum hypoosmolality and a high urine osmolality due to continuous sodium excretion. In this case, SIADH was probably induced by increased renal sensitivity to ADH and suspected high serum ANP level of unknown origin.
