Surveillance analysis on anaphylactic rash after immunization in Ouhai District of Wenzhou City, 2008-2013
- VernacularTitle:温州市瓯海区2008—2013年预防接种后过敏性皮疹监测分析
- Author:
Hong-Dan CHEN
1
;
Xian-Dan LIN
;
Li-Lin LIU
;
Wan-Cang LI
Author Information
1. 浙江省温州市瓯海区疾病预防控制中心
- Keywords:
Vaccination;
Anaphylactic rash;
Surveillance
- From:
Shanghai Journal of Preventive Medicine
2015;27(6):321-323
- CountryChina
- Language:Chinese
-
Abstract:
[ Objective ] To analyze the characteristics of anaphylactic rash after vaccination in Ouhai District of Wenzhou City during 2008-2013. [ Methods ] Data on anaphylactic rash cases reported during 2008-2013 were collected through the national AEFI information management system.And descriptive epidemiologic methodology was used in this study. [ Results] A total of 111 anaphylactic rash cases were reported in Ouhai District during 2008-2013,the reported incidence rate of anaphylactic rash were 3.58 per million doses.The ratio of male-female was 1.27:1.Cases of ≤1 year old accounted for 65.77%.Those without fever accounted for 75.68%.The number of the reports for the third quarter of the year accounted for 41.44%of the total.The cases of anaphylactic rash mostly occurred within 24 h after immunization(81.08%) .The top three vaccines reported in occurrence of rash were measles and rubella at-tenuated live vaccine(35.14%), diphtheria, tetanus and acellular pertussis combined vaccine(18.92%), and A(H1N1)influenza vaccine(5.41%).The reported rates for the top three vaccines were 115.85, 29.33,13.07 per million doses for 7-valent pneumococcal polysaccharide conjugate vaccine,measles and rubella combined attenuated live vaccine, A(H1N1) influenza vaccine,respectively. [Conclusion] Differential diagnosis of anaphylactic rashes needs to be more stressed.Most anaphylactic rash were reported in the expected range,but still monitoring analysis on incidence of allergic rash should be enhanced.Vac-cines with higher incidence of rash reported should be further studied and analyzed.