Serum levels of omentin in chronic hemodialysis patients and its related factors
- VernacularTitle:透析治疗的终末期肾病病人血浆网膜素水平及相关因素
- Author:
Juan SONG
1
;
Yan-Ni SUN
;
Jie YANG
;
Yi QIN
;
Jie CHEN
;
Jie-Jing CHENG
Author Information
1. 上海中医药大学附属普陀医院
- Keywords:
Omentin;
End-stage renal disease ( ESRD);
Diabetes
- From:
Shanghai Journal of Preventive Medicine
2015;(5):295-297
- CountryChina
- Language:Chinese
-
Abstract:
Objective] To investigate plasma level of omentin in chronic hemodialysis patients and its correlation with BMI,serum creatinine,fasting glucose,blood lipid and Homa-IR. [Methods] The study included 80 health people as control group and 62 chronic hemodialysis patients .A double antibody sandwich enzyme-linked immuno sorbent assay ( ELISA ) method was applied to detect the level of serum omentin and homeostasis model assessment of insulin resistant ( Homa-IR) to assess the insulin resistance index ,analysis being done on correlation between serum omentin and other indexes . [ Results ] The levels of plasma omentin was significantly higher in hemodialysis patients than those in control group ( P<0.01).ESRD(end-stage renal disease) patients with diabetes had lower level of plasma omentin than those without diabetes .The serum level of omentin had negative correlation with BMI and Homa-IR, and positive correlation with HDL-C, serum creatinine . [ Conclusion] The serum level of omentin proves to be ele-vated in ESRD patients receiving hemodialysis;and those with diabetes had lower levels of plasma omentin than those without .
