Review of mechanism on astragalus membranaceus in two-ways regulation of blood pressure
10.3760/cma.j.issn.1673-4246.2019.08.027
- VernacularTitle:黄芪双向调节血压的作用机制研究进展
- Author:
Yuqing ZHANG
1
;
Lei WANG
Author Information
1. 首都医科大学附属北京中医医院 100010
- Keywords:
Astragalus membranaceus;
Blood pressure;
Two-ways regulation;
Review
- From:
International Journal of Traditional Chinese Medicine
2019;41(8):907-910,封3
- CountryChina
- Language:Chinese
-
Abstract:
Astragalus membranaceus is one of the frequently used qi tonifying herbal medicines.It can regulate blood pressure.This paper reviewed the studies on the two-way regulation of blood pressure of Astragalus membranaceus in recent years,even thought the Astragalus membranaceus has been regarded to cure hyperhension due to qi deficiency.It can lower the pressure with large dosage or in liquid-fried form.Astragalus membranaceus,Astragalus membranaceus as the sovereign drug of the formulas or Astragalus membranaceus combined with western medicine can regulate blood pressure.It was found that the effect of reducing blood pressure was mainly related to the decrease of heart rate,dilation of blood vessels,inhibition of oxidative stress,reduction of calcium ion level,diuretics,change the content of growth factor and receptor,lowering uric acid,reduction of cysteine levels,and increase insulin sensitivity.Itelevated the blood pressure,mainly related to the increase of cardiac output and vasoconstriction.
