Medial temporal lobe epilepsy with hippocampal sclerosis
10.3760/cma.j.issn.1673-4408.2019.10.010
- VernacularTitle:内侧颞叶癫痫伴海马硬化的研究进展
- Author:
Jinying HUANG
1
Author Information
1. 中国医科大学附属盛京医院儿科
- Keywords:
Hippocampal sclerosis;
Classification;
Mechanism;
Imaging changes
- From:
International Journal of Pediatrics
2019;46(10):737-740
- CountryChina
- Language:Chinese
-
Abstract:
The medial temporal lobe epilepsy with hippocampal sclerosis is one of the most common drug resistant epilepsy,which involves complex neural networks and often requires surgical treatment.Studies have shown that it is related to the history of febrile convulsions,however,the further research is needed.Therefore,it is particularly important to accurately identify hippocampal sclerosis and guide clinical treatment.In this paper,the classification of hippocampal sclerosis was summarized,and the possible mechanism of hippocampal sclerosis was explored in terms of cationic-chloride co-transporters,glutamate and its receptors,and changes in expression of mRNA.The characteristics of magnetic resonance,magnetic resonance spectroscopy and PET of hippocampal sclerosis were listed to provide evidence for early recognition of hippocampal sclerosis.In theory,it provides ideas for further prevention of hippocampal sclerosis and improvement of quality of life in patients with medial temporal lobe epilepsy and hippocampal sclerosis.
