Cardiovascular system involvement of methylmalonic acidemia
10.3760/cma.j.issn.1673-4408.2019.10.003
- VernacularTitle:甲基丙二酸血症的心血管系统表现
- Author:
Lianshuang LIU
1
Author Information
1. 上海交通大学医学院附属上海儿童医学中心 200127
- Keywords:
Methylmalonic acidemia;
Cardiovascular system;
Structural heart disease;
Cardiomyopathy;
Pulmonary hypertension
- From:
International Journal of Pediatrics
2019;46(10):709-712
- CountryChina
- Language:Chinese
-
Abstract:
Methylmalonic acidemia is the most common disease of congenital organic acid metabolic disorders,and it is an autosomal recessive disease.The clinical manifestations of methylmalonic acidemia are non-specific.It is characterized by the neurological symptoms.Cardiovascular diseases have little been associated with methylmalonic acidemia.But,cardiovascular diseases including structural heart disease,pulmonary hypertension,cardiomyopathy,hypertension,arrhythmias,may cause rapid deterioration,or even sudden death.This paper is a review of cardiovascular diseases of methylmalonic acidemia.
