Research progress of decellularized extracellular matrix hydrogel in regenerative medicine.
10.7507/1001-5515.201907027
- Author:
Jingyu JIANG
1
;
Chi ZHANG
2
,
3
;
Tingxia ZHANG
1
;
Jiyuan ZHAO
1
Author Information
1. Key Laboratory of Pathophysiology and Technology Research, Medicine School, Ningbo University, Ningbo, Zhejiang 315211, P.R.China.
2. Key Laboratory of Pathophysiology and Technology Research, Medicine School, Ningbo University, Ningbo, Zhejiang 315211, P.R.China
3. Ningbo First Hospital, Ningbo, Zhejiang 315010, P.R.China.
- Publication Type:Journal Article
- Keywords:
decellularized extracellular matrix;
hydrogel;
regenerative medicine;
tissue engineering
- From:
Journal of Biomedical Engineering
2020;37(1):179-184
- CountryChina
- Language:Chinese
-
Abstract:
Decellularized extracellular matrix (dECM) has been widely used as a scaffold for regenerative medicine due to its high biomimetic and excellent biocompatibility. As a functional polymer material with high water content and controlled fluidity, hydrogel is very promising for some minimally invasive surgery in clinical practice. In recent years, with the rapid development of hydrogel theory and technology, dECM hydrogel has gradually become a research hotspot in the field of regenerative medicine. In this paper, the related researches in recent years are reviewed regarding the preparation of dECM hydrogel and its preclinical application. The future clinical use is also prospected.
