Epilepsy Surgery in Children versus Adults
- Author:
Ki Hyeong LEE
1
;
Yun Jin LEE
;
Joo Hee SEO
;
James E BAUMGARTNER
;
Michael WESTERVELD
Author Information
- Publication Type:Review
- Keywords: Epilepsy; Surgery; Drug resistant epilepsy; Child
- MeSH: Adult; Child; Drug Resistant Epilepsy; Epilepsy; Humans; Nervous System Diseases; Plastics; Quality of Life; Seizures
- From:Journal of Korean Neurosurgical Society 2019;62(3):328-335
- CountryRepublic of Korea
- Language:English
- Abstract: Epilepsy is one of the most common chronic neurological disorder affecting 6–7 per 1000 worldwide. Nearly one-third of patients with newly diagnosed epilepsy continue to have recurrent seizures despite adequate trial of more than two anti-seizure drugs : drug-resistant epilepsy (DRE). Children with DRE often experience cognitive and psychosocial co-morbidities requiring more urgent and aggressive treatment than adults. Epilepsy surgery can result in seizure-freedom in approximately two-third of children with improvement in cognitive development and quality of life. Understanding fundamental differences in etiology, co-morbidity, and neural plasticity between children and adults is critical for appropriate selection of surgical candidates, appropriate presurgical evaluation and surgical approach, and improved overall outcome.
