Validity and Reliability of the Korean Version of the Liverpool Adverse Events Profile (K-LAEP) in People with Epilepsy
- Author:
Jin Mo PARK
1
;
Jong Geun SEO
;
Sung Pa PARK
Author Information
1. Department of Neurology, Kyungpook National University School of Medicine, Daegu, Korea. sppark@mail.knu.ac.kr
- Publication Type:Original Article
- Keywords:
Epilepsy;
Antiepileptic drug;
Adverse event;
Validity;
Reliability
- MeSH:
Anticonvulsants;
Anxiety;
Cross-Sectional Studies;
Depression;
Epilepsy;
Humans;
Quality of Life;
Reproducibility of Results
- From:Journal of Korean Epilepsy Society
2012;16(2):43-48
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The aim of the study was to evaluate the validity and reliability of the Korean version of the Liverpool Adverse Events Profile (K-LAEP).METHODS: An observational, cross-sectional study was performed in people with epilepsy (PWE) treated with a stable dose of antiepileptic drugs (AEDs). The scale was translated from the English version into a Korean version and was then back-translated to examine its accuracy. Patients completed the K-LAEP, Quality of Life in Epilepsy-31 (QOLIE-31), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI).RESULTS: Three hundreds twelve patients were enrolled. The K-LAEP was completed in a short time, perceived as easy to comprehend, and there was no relevant information missing. Ceiling/floor effects were negligible. Internal consistency (Cronbach's alpha=0.9) and test-retest reliability (ICC=0.8) were satisfactory. The K-LAEP scores consistently correlated with QOLIE-31 (r= -0.528), BDI (r=0.526) and BAI (r=0.557) scores. When the K-LAEP was used to discriminate between patients with and without AED-related toxicity, the scores on the QOLIE, BDI and BAI corresponded. Anxiety symptoms were the strongest predictor to determine K-LAEP scores.CONCLUSIONS: The K-LAEP scale reveals highly acceptable parameters of the validity and reliability, suggesting that it is an appropriate instrument to measure adverse effects among Korean PWE.
