A Case of Malignant Glomus Tumor on Shoulder with Pulmonary Metastasis Treated with Doxorubicin and Ifosfamide in a 10-year Old Girl
10.15264/cpho.2016.23.1.65
- Author:
Won Seok JIN
1
;
In Sang JEON
Author Information
1. Department of Pediatrics, Graduate School of Medicine, Gachon University, Incheon, Korea. isjeon@gilhospital.com
- Publication Type:Case Report
- Keywords:
Malignant glomus tumor;
Chemotherapy
- MeSH:
Chemotherapy, Adjuvant;
Doxorubicin;
Drug Therapy;
Female;
Glomus Tumor;
Humans;
Ifosfamide;
Lung;
Neoplasm Metastasis;
Radiotherapy;
Shoulder
- From:Clinical Pediatric Hematology-Oncology
2016;23(1):65-69
- CountryRepublic of Korea
- Language:English
-
Abstract:
Malignant glomus tumor is an exceedingly rare neoplasm occurring in the soft tissues. Controversy exists over whether malignant glomus tumor is a true malignancy due to the rarity of metastasis, however, this neoplasm has been known to show relatively frequent metastasis and poor outcome. To improve the outcome of systemic therapy for malignant glomus tumor might be necessary, but the appropriate chemotherapy or radiotherapy has yet to be elucidated. We report a case of malignant glomus tumor with multiple pulmonary metastases treated with total surgical resection and adjuvant chemotherapy including doxorubicin and ifosfamide; however 7 months after completion of chemotherapy primary lung nodules increased. This case suggests that these chemotherapeutic agents are not effective for the management of malignant glomus tumor with metastasis.