A Case of Reticulohistiocytoma Mimicking Primary Cutaneous CD 4 Positive Small/medium T-cell Lymphoma
- Author:
Lira YOON
1
;
So Eun JUN
;
Jung Ho SEO
;
Young Tak LIM
Author Information
1. Department of Pediatrics, Pusan National University College of Medicine, Busan, Korea. newwife99@hanmail.net
- Publication Type:Case Report
- Keywords:
Reticulohistiocytoma;
Solitary epithelioid histiocytoma;
Skin;
Palm
- MeSH:
Cytoplasm;
Diagnosis, Differential;
Eosinophils;
Female;
Histiocytosis, Non-Langerhans-Cell;
Humans;
Infant;
Lymphoma, T-Cell;
Nuclear Envelope;
Skin
- From:Clinical Pediatric Hematology-Oncology
2014;21(2):153-156
- CountryRepublic of Korea
- Language:English
-
Abstract:
Reticulohistiocytoma is a rare, benign histiocytic proliferation of the skin or soft tissue. A 5-month-old healthy girl visited our clinic for an enlarging nodule on the center of her right palm. The clinical differential diagnosis included xanthogranuloma and primary cutaneous CD4 positive small/medium T-cell lymphoma. Histopathology of the nodule showed abundant eosinophilic and glassy cytoplasm. The nuclei were round to oval shaped, with focal irregular nuclear membrane, and mitotic figures were absent. Immunohistochemical study determined that the cells were positive for CD68 but negative for CD1a. She was finally diagnosed with reticulohistiocytoma (solitary epithelioid histiocytoma).
