An Adolescent Case of Castleman Disease of the Plasma Cell Type Treated with Radiotherapy
- Author:
Tae Hoon HEO
1
;
Hyun Wook LIM
;
Ji Hyun SIM
;
Jung Hwa LEE
;
Eun Hee LEE
;
Kwang Chul LEE
Author Information
1. Department of Pediatrics, Korea University College of Medicine, Seoul, Korea. kwcl5609@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Castleman disease;
Child;
Lymphoproliferative disorders;
Radiotherapy;
Case reports
- MeSH:
Adolescent;
Child;
Giant Lymph Node Hyperplasia;
Humans;
Hyperplasia;
Lymphoproliferative Disorders;
Male;
Plasma Cells;
Radiotherapy;
Thorax
- From:Clinical Pediatric Hematology-Oncology
2014;21(2):157-162
- CountryRepublic of Korea
- Language:English
-
Abstract:
Castleman disease (CD) is a disorder with distinct lymphoid hyperplasia of unknown origin, and it is rare in children. There are two major forms of CD: unicentric (localized) and multicentric. Pathologically, it can be categorized into three subtypes: hyaline- vascular, plasma cell, and mixed types. We experienced a 15-year-old boy with histopathologically proven mediastinal CD of the plasma cell type. He was referred to our hospital because of mediastinal widening in a chest x-ray found by chance. Surgery was performed to resect two right paratracheal masses and subtotal excision was done. As complete surgical resection was not possible, the patient subsequently received three-dimensional conformal radiation therapy (total 5,400 cGy in 27 fractions). The size of the mass decreased, and his clinical symptoms regressed without any side effects from radiotherapy. Here we report a case of unicentric plasma cell type CD, treated with radiotherapy due to incomplete surgical resection.
