A Case of Appendicitis with Liver Abscesses Developed during Allogeneic Hematopoietic Stem Cell Transplantation
- Author:
Seul Bee LEE
1
;
Jung Min LEE
;
Sun Wha LEE
;
Eun Sun YOO
;
Kyung Ha RYU
Author Information
1. Department of Pediatrics, Ewha Womans University School of Medicine, Seoul, Korea. ykh@ewha.ac.kr
- Publication Type:Case Report
- Keywords:
Allogneic hematopoietic stem cell transplantation;
Appendicitis;
Neutropenic patients;
Liver abscess;
Typhlitis
- MeSH:
Abdominal Pain;
Anemia, Aplastic;
Anti-Bacterial Agents;
Antifungal Agents;
Appendectomy;
Appendicitis;
Child;
Cyclophosphamide;
Diagnosis;
Drainage;
Drug Therapy;
Fever;
Hematopoietic Stem Cell Transplantation;
Humans;
Immunoglobulins;
Liver Abscess;
Male;
Stem Cell Transplantation;
Typhlitis
- From:Clinical Pediatric Hematology-Oncology
2014;21(2):172-176
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 10-year-old boy with severe aplastic anemia was admitted for allogeneic hematopoietic stem cell transplantation. After conditioning chemotherapy using cyclophosphamide, fludarabine, and antithymocyte immunoglobulin, he presented with fever and abdominal pain on day 0 of stem cell transplantation. After diagnosis of acute appendicitis with minor perforation, appendectomy was performed just after cell infusion. A week after the procedure, he showed two huge liver abscesses in S4 and S6 segments. We used broad spectrum antibiotics along with antifungal agents. Percutaneous drainage was attempted, but no fluid was removed and no microorganisms were isolated. After 7 weeks of antibiotics and antifungal therapy, liver abscesses showed improvement. We report a case of successfully treated appendicitis with liver abscesses in a severely neutropenic patient during allogeneic hematopoietic stem cell transplantation.
