Mucoepidermoid Carcinoma on Submandibular Salivary Gland as a Second Malignant Neoplasm after Treatment of Yolk Sac Tumor
- Author:
Hyun Sup KEUM
1
;
Jung In KANG
;
Eun Sun YOO
;
Hee Jung PARK
;
Sun Wha LEE
;
Kyung Ha RYU
Author Information
1. Department of Pediatrics, Ewha Womans University School of Medicine, Seoul, Korea. ykh@ewha.ac.kr
- Publication Type:Case Report
- Keywords:
Second malignant neoplasm;
Mucoepidermoid carcinoma
- MeSH:
Abdomen;
Carcinoma, Mucoepidermoid;
Child;
Diagnosis;
Drug Therapy;
Endodermal Sinus Tumor;
Female;
Humans;
Korea;
Neoplasm Metastasis;
Peripheral Blood Stem Cell Transplantation;
Radiotherapy;
Salivary Gland Neoplasms;
Salivary Glands;
Submandibular Gland;
Writing
- From:Clinical Pediatric Hematology-Oncology
2014;21(2):177-180
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Malignant salivary gland tumors only represent 0.08% of all childhood tumors and mucoepidermoid carcinoma (MEC) is the most common histologic type. Although there are many reports describing second malignant neoplasm (SMN) in patients treated for childhood cancer, salivary gland tumors rarely appears. In Korea, there has been no report about MEC that developed in children as a SMN. We report a MEC in a 4 years and 8 months old female child that developed after completing treatment for yolk sac tumor of lower abdomen. The primary tumor presented with metastasis at the time of diagnosis, and therefore, the child underwent high-dose chemotherapy with autologous peripheral blood stem cell transplantation along with surgery and radiotherapy. Three years and five months after completing treatment, MEC developed in her submandibular gland. She was treated with surgery and radiotherapy and is in disease free state for 5 months at the time of this writing.
