A Case of Glanzmann's Thrombasthenia Successfully Managed after Tonsillectomy
- Author:
Jeong Seok CHOI
1
;
Gi Hwa JUNG
;
Jae Yol LIM
;
Young Mo KIM
;
Soon Ki KIM
Author Information
1. Department of Otorhinolaryngology-Head & Neck Surgery, Inha University School of Medicine, Incheon, Korea.
- Publication Type:Case Report
- Keywords:
Glanzmann's thrombasthenia;
Tonsillectomy;
Hemostasis
- MeSH:
Blood Platelets;
Child;
Epistaxis;
Factor VIIa;
Female;
Fibrin Tissue Adhesive;
Hemorrhage;
Hemostasis;
Humans;
Male;
Membranes;
Menorrhagia;
Platelet Aggregation;
Purpura;
Thrombasthenia;
Tonsillectomy
- From:Clinical Pediatric Hematology-Oncology
2014;21(1):29-32
- CountryRepublic of Korea
- Language:English
-
Abstract:
Glanzmann's thrombasthenia (GT) is a rare autosomal recessive disease and platelet function disorder, in which platelet membrane GP IIb/ IIIa complex is defective and platelet aggregation is undeveloped. GT is characterized by mucocutaneous hemorrhages, such as, epistaxis, purpura, gingival bleeding, and menorrhagia, severe bleeding complications during surgery. We report the case of a 6-year-old boy with GT who underwent tonsillectomy. Here, we focus on perioperative hemostatic management using recombinant factor VIIa, fibrin glue and hemostat materials.