Growing Teratoma Syndrome of the Pineal Gland Recognized Very Early during Chemotherapy in a Child with a Non-Germinomatous Germ-Cell Tumor
- Author:
Zhaoxia ZHANG
1
;
Byung Gyu YOON
;
Hee Jo BAEK
;
Sun Ju PARK
;
Dong Kyun HAN
;
Soo Min PARK
;
Tae Young JUNG
;
Min Cheol LEE
;
Hoon KOOK
Author Information
1. Department of Pediatrics, Chonnam National University Hwasun Hospital, Hwasun-gun, Korea. hoonkook@chonnam.ac.kr
- Publication Type:Case Report
- Keywords:
Growing teratoma syndrome;
Non-germinomatous germ cell tumors;
Immature teratoma
- MeSH:
Child;
Combined Modality Therapy;
Humans;
Pineal Gland;
Puberty, Precocious;
Teratoma
- From:Clinical Pediatric Hematology-Oncology
2013;20(1):75-78
- CountryRepublic of Korea
- Language:English
-
Abstract:
The growing teratoma syndrome (GTS) is defined as the development of mature low-grade elements in the absence of a recurrent non-germinomatous germ-cell tumor (NGGCT) after partial response to multimodal treatment. It is uncommon and may occur in intracranial NGGCTs. Here, we report that a 7-year-old boy with intracranial NGGCT presented with precocious puberty and developed growing teratoma syndrome only 2 weeks after the first cycle of chemotherapy.
