A Case Report of Botryoid Wilms Tumor: Has Different Clinical Manifestations
- Author:
Jinkyung SUH
1
;
Ye Jee SHIM
;
Jin Young PARK
;
Po Eun PARK
;
Gil Suk YOON
;
Kun Soo LEE
Author Information
1. Department of Pediatrics, Kyungpook National University College of Medicine, Daegu, Korea. kslee@knu.ac.kr
- Publication Type:Case Report
- Keywords:
Wilms tumor;
Botryoid;
Hematuria
- MeSH:
Anaplasia;
Chemotherapy, Adjuvant;
Fever;
Follow-Up Studies;
Hematuria;
Humans;
Infant;
Kidney;
Kidney Neoplasms;
Kidney Pelvis;
Muscle, Skeletal;
Recurrence;
Ureter;
Vincristine;
Vomiting;
Wilms Tumor
- From:Clinical Pediatric Hematology-Oncology
2012;19(2):123-127
- CountryRepublic of Korea
- Language:English
-
Abstract:
A previously healthy, 16-month-old boy was admitted to hospital due to fever, vomiting, and persistent gross hematuria for 2 weeks. His imaging studies showed an inhomogeneous mass, in a left dilated renal pelvis and proximal ureter, which was suggestive of a kidney neoplasm. A stage I Wilms tumor limited to the nephrectomised kidney was diagnosed by histology. The margin of ureter and renal vessels were clear. There was no evidence of anaplasia, angiolymphatic invasion, or skeletal muscle differentiation. In addition, there were polypoid protrusions of tumor into the pelvicaliceal system, resulting in such a 'botryoid' appearance. The patient had been treated with adjuvant chemotherapy using 7 cycles of intravenous actinomycin-D and vincristine (NWTS regimen EE4A) for 5 months. During a 22-month follow-up period, there has been no evidence of tumor recurrence.