A Adrenocortical Oncocytoma in a 10-year-old Girl Presenting with Virilization
- Author:
Tae Min EOM
1
;
Mi Kyoung KIM
;
Sun Hee LEE
;
Woo Yeong CHUNG
;
Ji Kyoung PARK
;
Soo Jin JUNG
;
Jae Ho SHIN
Author Information
1. Department of Pediatrics, College of Medicine, Inje University, Busan, Korea. pjk4285@hanmail.net
- Publication Type:Case Report
- Keywords:
Adrenocortical oncocytoma;
Children;
Virilization
- MeSH:
Adenoma, Oxyphilic;
Adrenalectomy;
Adult;
Child;
Cytoplasm;
Dehydroepiandrosterone Sulfate;
Eosinophils;
Hair;
Humans;
Mitochondria;
Plasma;
Testosterone;
Virilism;
Voice
- From:Clinical Pediatric Hematology-Oncology
2012;19(2):128-131
- CountryRepublic of Korea
- Language:English
-
Abstract:
Adrenocortical oncocytoma is a rare epithelial tumor only described in adults and in most cases, benign and non-functioning. Histologically characterized by cells with eosinophilic granular cytoplasm and ultra-structurally by the presence of numerous closely packed mitochondria. We report a case of adrenal oncocytoma developed in a 10-year-old girl who presented a left adrenal mass with low voice tone, excessive hair growth, and elevation of the plasma testosterone and dehydroepiandrosterone sulfate levels as a result of overproduction of adrenal steroid hormones. After the left adrenalectomy, her hormone levels were normalized.
