Clinical Features and Treatment Outcomes of Hemangioma in a Single Institution
- Author:
Sun Hee CHUNG
1
;
Dong Hyuk PARK
;
Jae Won SHIM
;
Duk Soo KIM
;
Jung Yeon SHIM
;
Moon Soo PARK
;
Hye Lim JUNG
;
Hong Hoe KOO
Author Information
1. Department of Pediatrics, Sungkyunkwan University School of Medicine, Seoul, Korea. hl.jung@samsung.com
- Publication Type:Original Article
- Keywords:
Hemangioma;
Propranolol
- MeSH:
Female;
Head;
Hemangioma;
Humans;
Interferons;
Neck;
Parturition;
Propranolol;
Retrospective Studies;
Sex Ratio
- From:Clinical Pediatric Hematology-Oncology
2011;18(1):34-39
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Hemangiomas are the most common benign tumor of childhood. Uncertainties regarding their diagnosis or management often prompt life- or function-threatening complications or unnecessary treatment. The objective of this study is to analyze and understand the clinical features and treatment outcomes of hemangiomas for accurate diagnosis and treatment.METHODS: A retrospective chart review of 60 patients diagnosed as hemangioma in Kangbuk Samsung Hospital from January 2001 to January 2011 was performed.RESULTS: Hemangiomas were observed predominantly in female with the sex ratio of 1:2.2. They were present at birth in 32%, and within 2 months of age in 22% of the patients. In 45% of the patients, hemangiomas occurred on the head and neck, which were the most commonly involved site. 27% of the cases were clinically diagnosed, 40% of the cases were diagnosed after imaging studies, and 37% of cases were confirmed by histopathology. 40% of the patients were observed without treatment. 57% of the patients were treated with surgical excision, corticosteroid, interferon or propranolol. Eight patients were treated with oral propranolol, and seven of them demonstrated regression without major side effects.CONCLUSION: We confirmed that hemangiomas were preponderant in female and usually appeared in first 2 months of life, and the head and neck were the most favored site. We observed that propranolol was effective and safe for treating problematic infantile hemangiomas.
