- Author:
Kim Cuc Thi NGUYEN
1
;
Kyung A CHO
Author Information
- Publication Type:Review
- Keywords: Caveolin 1; Caveolae; Cell Aging; Endocytosis
- MeSH: Caveolae; Caveolin 1; Cell Aging; Cell Membrane; Endocytosis
- From:Chonnam Medical Journal 2017;53(1):28-36
- CountryRepublic of Korea
- Language:English
- Abstract: Caveolin-1 (Cav-1) is a trans-membrane protein that is a major component of the caveolae structure on the plasma membrane. Cav-1 is involved in the regulation of various cellular processes, including cell growth, differentiation, endocytosis, and in particular it has been implied in cellular senescence. Here we review current knowledge about Cav-1 in cellular signaling and discuss the role of Cav-1 in aging-related diseases.