Cutaneous Melanoma in Asians
10.4068/cmj.2016.52.3.185
- Author:
Sang Yub KIM
1
;
Sook Jung YUN
Author Information
1. Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea. sjyun@chonnam.ac.kr
- Publication Type:Review
- Keywords:
Melanoma, Cutaneous Malignant;
Hutchinson's Melanotic Freckle;
Nails;
Melanoma
- MeSH:
Asian Continental Ancestry Group;
Foreign Bodies;
Hematoma;
Humans;
Hutchinson's Melanotic Freckle;
Melanoma;
Mortality;
Rare Diseases;
Skin Neoplasms;
Ulcer;
Warts
- From:Chonnam Medical Journal
2016;52(3):185-193
- CountryRepublic of Korea
- Language:English
-
Abstract:
Malignant melanoma is a rare disease in Asians but potentially the most aggressive form of skin cancer worldwide. It can occur in any melanocyte-containing anatomic site. Four main cutaneous melanoma subtypes are recognized: lentigo maligna melanoma, superficial spreading melanoma, acral lentiginous melanoma (ALM), and nodular melanoma. Generally, excessive exposure to ultraviolet (UV) radiation increases the risk of melanoma. The exception is ALM, which is the most common melanoma subtype in Asians and is not associated with UV radiation. ALM presents as dark brownish to black, irregular maculopatches, nodules, or ulcers on the palms, soles, and nails. The lesions may be misdiagnosed as more benign lesions, such as warts, ulcers, hematomas, foreign bodies, or fungal infections, especially in amelanotic acral melanomas where black pigments are absent. The aim of this brief review is to improve understanding and the rate of early detection thereby reducing mortality, especially regarding cutaneous melanoma in Asians.