A Case of Membranous Glomerulonephritis with Superimposed Anti-Neutrophil Cytoplasmic Antibody-Associated Rapidly Progressive Crescentic Glomerulonephritis
10.4068/cmj.2015.51.2.102
- Author:
Yoo Hyung KIM
1
;
Hae Ri KIM
;
Young Rok HAM
;
Jae Woong JEON
;
Sarah CHUNG
;
Dae Eun CHOI
;
Kang Wook LEE
;
Ki Ryang NA
Author Information
1. Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea. drngr@cnu.ac.kr
- Publication Type:Case Report
- Keywords:
Glomerulonephritis;
Membranes;
Antibodies;
Anti-neutrophil cytoplasmic antibody-associated vasculitis
- MeSH:
Adult;
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis;
Antibodies;
Antibodies, Antineutrophil Cytoplasmic;
Cytoplasm;
Glomerulonephritis;
Glomerulonephritis, Membranous;
Humans;
Hypertension, Malignant;
Korea;
Lupus Nephritis;
Membranes;
Proteinuria;
Renal Veins;
Thrombosis
- From:Chonnam Medical Journal
2015;51(2):102-105
- CountryRepublic of Korea
- Language:English
-
Abstract:
Idiopathic membranous glomerulonephritis (IMGN) is commonly diagnosed in adults with proteinuria. Rapid deterioration of renal function is a rare complication of IMGN, except when accompanied by renal vein thrombosis, malignant hypertension, or other underlying disease, including lupus nephritis. Here, we present a case of rapid deterioration of renal function in a patient with MGN superimposed with anti-neutrophil cytoplasmic antibody (ANCA)-associated rapidly progressive crescentic glomerulonephritis (RPGN). Overall, about 20 cases of MGN with ANCA-associated RPGN have been reported. This case of biopsy-proven MGN with ANCA-associated RPGN is the first to be reported in Korea.