Clinical Effect of a Mixed Solution of Sodium Hyaluronate and Sodium Carboxymethylcellulose During the Transconjunctival Approach for Orbital Wall Reconstruction
10.4068/cmj.2012.48.2.123
- Author:
Byung Wan KANG
1
;
Hyo Seok LEE
;
Han Jin OH
;
Kyung Chul YOON
Author Information
1. Department of Ophthalmology, Research Institute of Medical Sciences, Chonnam National University Medical School and Hospital, Gwangju, Korea. kcyoon@jnu.ac.kr
- Publication Type:Original Article
- Keywords:
Eyelid retraction;
Eyelids;
Orbital fractures
- MeSH:
Carboxymethylcellulose Sodium;
Ectropion;
Eyelids;
Humans;
Hyaluronic Acid;
Muscles;
Orbit;
Orbital Fractures;
Postoperative Period;
Prospective Studies;
Reflex;
Sodium
- From:Chonnam Medical Journal
2012;48(2):123-127
- CountryRepublic of Korea
- Language:English
-
Abstract:
This study aimed to evaluate the anti-adhesive effect of a mixed solution of sodium hyaluronate and sodium carboxymethylcellulose (HACMC, Guardix-sol(R)) during the transconjunctival approach to orbital wall reconstruction. Eighty-seven patients who underwent orbital wall reconstruction by the transconjunctival approach were enrolled in this prospective study. We applied HACMC between the orbicularis oculi muscle and the orbital septum after surgery in 47 patients and did not use it in 40 patients. Lower lid retraction and marginal reflex distance 2 (MRD2) were measured to analyze the degree of postoperative adhesion at 1 week and 1, 3, and 6 months. The degree of MRD2 showed clinically significant differences at postoperative 1 week and 1 month between the HACMC and control groups (p<0.05). Lower lid ectropion developed in two patients (5.0%) in the control group but did not occur in the HACMC group. In orbital wall reconstruction by the transconjunctival approach, the HACMC mixture solution is effective for preventing adhesion and lower lid ectropion during the early postoperative period.
