Comparison of invasive dynamic blood pressure between superior mesenteric artery and common carotid artery in rats
10.5847/wjem.j.1920-8642.2020.02.007
- Author:
Rui-ning Liu
1
;
Xiao-jun Wei
1
;
Shao-ping Li
1
;
Cheng Jiang
1
;
Yan Zhao
1
Author Information
1. Emergency Department of Zhongnan Hospital, Wuhan University, Wuhan 430071, China
- Publication Type:Journal Article
- Keywords:
Blood pressure;
Superior mesenteric artery;
Common carotid artery;
Abdominal aorta
- From:
World Journal of Emergency Medicine
2020;11(2):102-108
- CountryChina
- Language:English
-
Abstract:
BACKGROUND: The purpose of this study was to identify the consistency of invasive dynamic blood pressure (BP) monitoring between the superior mesenteric artery (SMA) and the common carotid artery (CCA).
METHODS: Eight male Sprague-Dawley rats were cannulated in SMA and CCA simultaneously for BP monitoring, respectively. The abdominal aorta was prepared for the induction of BP change through clamping/de-clamping by a microvascular clip. The dynamic BP monitoring was performed by a polygraph system. Systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP) values would be recorded during different time periods: the baseline (T1), the increasing period after clamping (T2), the platform period during clamping (T3), the decreasing period after de-clamping (T4), and the final platform period (T5). Three trials were performed on each rat with 15-minute intervals between consecutive monitoring.
RESULTS: Systolic BP showed no significant differences between SMA and CCA. However, significant difference was found in diastolic blood pressure except at T5 (P=0.534). Mean arterial pressure of two arteries were signifi cantly different only at T1 (P=0.015). The strength of association was significantly high between BP measurements through SMA and CCA (P<0.001). The Bland- Altman analyses showed that mean bias of MAP changed no more than 5 mmHg and standard deviation less than 8 mmHg during T2 and T4, respectively.
CONCLUSION: The study indicates SMA might be an alternative site for invasive BP monitoring during abdominal aorta occlusion and release, especially in cerebrovascular-related research.
