Association between Hyperuricemia and Health-Related Quality of Life in Korean Adults: Based on the Seventh Korean National Health and Nutrition Examination Survey (2016–2017)
10.21215/kjfp.2019.9.6.532
- Author:
Zee Hae BANG
1
;
Yeon Ji LEE
;
Ji Ho CHOI
;
Yoohyun KIM
;
Sung Hee AN
;
Min Kyoung LEE
;
Sangsook LEE
Author Information
1. Department of Family Medicine, Inha University College of Medicine, Incheon, Korea. dawndusk@naver.com
- Publication Type:Original Article
- Keywords:
Serum Uric Acid;
Hyperuricemia;
Health-Related Quality of Life;
Adults
- MeSH:
Adult;
Cardiovascular Diseases;
Diabetes Mellitus, Type 2;
Female;
Humans;
Hypertension;
Hyperuricemia;
Korea;
Logistic Models;
Male;
Nutrition Surveys;
Odds Ratio;
Prevalence;
Quality of Life;
Renal Insufficiency, Chronic;
Uric Acid
- From:
Korean Journal of Family Practice
2019;9(6):532-538
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The prevalence of hyperuricemia has increased over the past few decades. Hyperuricemia is responsible for the increased risk of hypertension, type 2 diabetes mellitus, chronic renal disease, and cardiovascular disease. Health-related quality of life (HQoL) has been increasingly used as an outcome in clinical trials, effectiveness research, and research on quality of care. Therefore, we aimed to analyze the association between hyperuricemia and HQoL in Korean adults aged >19 years.METHODS: We included 2,376 male and 2,593 female who participated in the Korea National Health and Nutrition Examination Survey from 2016 to 2017. Hyperuricemia was defined as a serum uric acid (SUA) level of 7 mg/dL. The Euro quality of life-5 dimension (EQ-5D) questionnaire was used to measure HQoL. A multiple logistic regression analysis was performed to examine the association between hyperuricemia and HQoL.RESULTS: The EQ-5D index score of the hyperuricemia group was significantly lower than of the healthy group. After adjusting for multiple covariates, the odds ratio (95% confidence interval, [CI]) for mobility issues was 1.46 (95% CI, 1.211–1.683) in male and 1.33 (95% CI, 0.716–2.464) in female; however, the difference was not statistically significant for female.CONCLUSION: Hyperuricemia was associated with reduced quality of life. It is important to control SUA levels to improve HQoL.
