Association between Metabolic Syndrome and Severity of Depression Scored with Patient Health Questionnaire-9 in Men Older Than 50 Years
10.21215/kjfp.2019.9.5.467
- Author:
Minsik LEE
1
Author Information
1. Department of Family Medicine, Serim General Hospital, Incheon, Korea. misrandil15749@gmail.com
- Publication Type:Original Article
- Keywords:
Metabolic Syndrome;
National Institutes of Health;
Depression;
Patient Health Questionnaire;
The Sixth Korea National Health and Nutrition Examination Survey
- MeSH:
Blood Pressure;
Body Mass Index;
Centers for Disease Control and Prevention (U.S.);
Cholesterol;
Depression;
Education;
Fasting;
Glucose;
Humans;
Korea;
Lipoproteins;
Male;
National Institutes of Health (U.S.);
Nutrition Surveys;
Odds Ratio;
Prevalence;
Triglycerides;
Waist Circumference
- From:
Korean Journal of Family Practice
2019;9(5):467-470
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: This study aimed to evaluate the association between metabolic syndrome and depression severity based on the Patient Health Questionnaire 9 (PHQ-9) score in men aged >50 years.METHODS: In this study, we used data of 1,230 individuals from the Sixth Korea National Health and Nutrition Examination Survey (KNHANES VII-1) 2016 conducted by the Korea Centers for Disease Control and Prevention. We diagnosed metabolic syndrome in accordance with National Cholesterol Education Program-Adult Treatment Panel III guidelines using waist circumference, blood pressure, fasting serum triglyceride level, high-density lipoprotein cholesterol level, and fasting glucose level in men aged >50 years (mean±standard deviation: 64.6±8.8 years), and their PHQ-9 scores were classified as mild and severe (cutoff, 10).RESULTS: The mean waist circumference, fasting glucose level, triglyceride level, and high-density lipoprotein cholesterol level were 87.1±8.2 cm, 109.8±28.3 mg/dL, 155.9±123.9 mg/dL, and 46.5±12.2 mg/dL, respectively. The mean systolic and diastolic blood pressures were 124.7±15.9 mmHg and 76.2±10.7 mmHg, respectively. The mean body mass index, was 24.2±2.9 kg/m². The prevalence of metabolic syndrome was 43.7%. The mean PHQ-9 score was 2.0±3.3. The prevalence of severe depression with a score of >10 was 4.2%. Metabolic syndrome and depression were related (P<0.05). The adjusted odds ratio for metabolic syndrome was 0.5 (95% confidence interval [CI], 0.3–0.9). However, age (95% CI, 0.9–1.0), sleep duration during weekdays (95% CI, 0.9–1.0), and sleep duration during weekends (95% CI, 0.9–1.0) were not related.CONCLUSION: Metabolic syndrome was associated with depression in men aged >50 years in this study.